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1st International Conference on Science and Technology, ICOST 2019, 2-3 May, Makassar, Indonesia

Research Article

Dynamics of Macrofages and Cytokines after Myocardial Infarction

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  • @INPROCEEDINGS{10.4108/eai.2-5-2019.2284674,
        author={Usman  Pagalay and Luluk  Handayani and Abdullah  Azzam},
        title={Dynamics of Macrofages and Cytokines after Myocardial Infarction },
        proceedings={1st International Conference on Science and Technology, ICOST 2019, 2-3 May, Makassar, Indonesia},
        publisher={EAI},
        proceedings_a={ICOST},
        year={2019},
        month={6},
        keywords={mathematical model macrophage cytokines myocardial infraction},
        doi={10.4108/eai.2-5-2019.2284674}
    }
    
  • Usman Pagalay
    Luluk Handayani
    Abdullah Azzam
    Year: 2019
    Dynamics of Macrofages and Cytokines after Myocardial Infarction
    ICOST
    EAI
    DOI: 10.4108/eai.2-5-2019.2284674
Usman Pagalay1,*, Luluk Handayani1, Abdullah Azzam1
  • 1: Department of Mathematics, Faculty of Science and Technology, Universitas Islam Negeri Maulana Malik Ibrahim Malang, Indonesia. 65144
*Contact email: usmanpagalay@yahoo.co.id

Abstract

The mathematical model of populations of Macrophages and Cytokines after Myocardial Infraction explains the macrophages activation following by cytokines secretion in the left ventricle. Those models appears to be a system of six simultaneous non-linear ordinary differential equations, involving inactivated macrophages Mu (t), classical activated macrofages M1 (t), alternative activated macrophages M2 (t), interleukin-10 I10 (t), TNF-α Tα (t) and interleukin-1 I1 (t). The method used in this article is numerical Runge-Kutta method with computer assistance for obtaining the numerical solution and gathering several informations including the crucials of cytokines on the development of macrophages.

Keywords
mathematical model macrophage cytokines myocardial infraction
Published
2019-06-14
Publisher
EAI
http://dx.doi.org/10.4108/eai.2-5-2019.2284674
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