Research Article
Dynamics of Macrofages and Cytokines after Myocardial Infarction
@INPROCEEDINGS{10.4108/eai.2-5-2019.2284674, author={Usman Pagalay and Luluk Handayani and Abdullah Azzam}, title={Dynamics of Macrofages and Cytokines after Myocardial Infarction }, proceedings={1st International Conference on Science and Technology, ICOST 2019, 2-3 May, Makassar, Indonesia}, publisher={EAI}, proceedings_a={ICOST}, year={2019}, month={6}, keywords={mathematical model macrophage cytokines myocardial infraction}, doi={10.4108/eai.2-5-2019.2284674} }- Usman Pagalay
Luluk Handayani
Abdullah Azzam
Year: 2019
Dynamics of Macrofages and Cytokines after Myocardial Infarction
ICOST
EAI
DOI: 10.4108/eai.2-5-2019.2284674
Abstract
The mathematical model of populations of Macrophages and Cytokines after Myocardial Infraction explains the macrophages activation following by cytokines secretion in the left ventricle. Those models appears to be a system of six simultaneous non-linear ordinary differential equations, involving inactivated macrophages Mu (t), classical activated macrofages M1 (t), alternative activated macrophages M2 (t), interleukin-10 I10 (t), TNF-α Tα (t) and interleukin-1 I1 (t). The method used in this article is numerical Runge-Kutta method with computer assistance for obtaining the numerical solution and gathering several informations including the crucials of cytokines on the development of macrophages.
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