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airo 25(1):

Research Article

Explainable AI Based Deep Ensemble Convolutional Learning for Multi-Categorical Ocular Disease Prediction

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  • @ARTICLE{10.4108/airo.9234,
        author={Abu Kowshir Bitto  and Rezwana Karim  and Mst Halema Begum and Md Fokrul Islam Khan Khan and Dr. Md. Maruf Hassan  and Prof. Dr. Abdul kadar Muhammad Masum },
        title={Explainable AI Based Deep Ensemble Convolutional Learning for Multi-Categorical Ocular Disease Prediction},
        journal={EAI Endorsed Transactions on AI and Robotics},
        volume={4},
        number={1},
        publisher={EAI},
        journal_a={AIRO},
        year={2025},
        month={7},
        keywords={Eye Disease, Deep Ensemble Learning , Transfer Learning , Explainable AI, Ocular Disease},
        doi={10.4108/airo.9234}
    }
    
  • Abu Kowshir Bitto
    Rezwana Karim
    Mst Halema Begum
    Md Fokrul Islam Khan Khan
    Dr. Md. Maruf Hassan
    Prof. Dr. Abdul kadar Muhammad Masum
    Year: 2025
    Explainable AI Based Deep Ensemble Convolutional Learning for Multi-Categorical Ocular Disease Prediction
    AIRO
    EAI
    DOI: 10.4108/airo.9234
Abu Kowshir Bitto 1, Rezwana Karim 1, Mst Halema Begum2, Md Fokrul Islam Khan Khan2, Dr. Md. Maruf Hassan 3, Prof. Dr. Abdul kadar Muhammad Masum 3,*
  • 1: Daffodil International University
  • 2: International American University
  • 3: Southeast University
*Contact email: akmmasum@yahoo.com

Abstract

Diseases of the eye such as diabetic retinopathy, glaucoma, and cataract remain among the leading causes of blindness and vision impairment worldwide. Diagnosis in its early stages followed by early treatment is crucial to preventing permanent loss of vision. Recent advances in Artificial Intelligence (AI), particularly Transfer Learning and Explainable AI (XAI), have proven highly promising in automating the identification of retinal pathologies from medical images. In this paper, we propose an ensemble deep learning approach that integrates four pre-trained convolutional neural networks, i.e., VGG16, MobileNet, DenseNet, and InceptionV3, to classify retinal images into four categories: diabetic retinopathy, glaucoma, cataracts, and normal. The ensemble method leverages the power of multiple models to improve classification accuracy. Additionally, Explainable AI techniques are applied to make the model more interpretable, with visual explanations and insights into AI system decision-making and thereby establishing clinical trust and reliability. The system is evaluated on a new benchmarked eye disease dataset used from Hugging Face, and the results in terms of accuracy and model transparency are encouraging. This research contributes towards developing reliable, explainable, and efficient AI-driven diagnostic systems to assist healthcare professionals in the early detection and management of eye diseases

Keywords
Eye Disease, Deep Ensemble Learning , Transfer Learning , Explainable AI, Ocular Disease
Received
2025-05-03
Accepted
2025-07-05
Published
2025-07-28
Publisher
EAI
http://dx.doi.org/10.4108/airo.9234

Copyright © 2025 Abu Kowshir Bitto et al., licensed to EAI. This is an open access article distributed under the terms of the CC BYNC-SA 4.0, which permits copying, redistributing, remixing, transformation, and building upon the material in any medium so long as the original work is properly cited.

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