Research Article
Tract-Based Spatial Statistics Analysis of Diffusion-Tensor Imaging Data in Patients with Small Cell Lung Cancer.
@INPROCEEDINGS{10.4108/icst.mobihealth.2014.257513, author={Sofia Benezi and Eustratios Karavasilis and Irene Karanasiou and George Matsopoulos and Eric Ventouras and Nikolaos Uzunoglu and Vasilios Kouloulias and Matilda Papathanasiou and Adreas Foteineas and Theodore Soldatos and Christin Iosif and Efstathios Efstathopoulos and Nikolaos Kelekis and Dimitrios Kelekis}, title={Tract-Based Spatial Statistics Analysis of Diffusion-Tensor Imaging Data in Patients with Small Cell Lung Cancer.}, proceedings={4th International Conference on Wireless Mobile Communication and Healthcare - "Transforming healthcare through innovations in mobile and wireless technologies"}, publisher={IEEE}, proceedings_a={MOBIHEALTH}, year={2014}, month={12}, keywords={diffusion tensor imaging dti tract- based spatial statistics tbss small cell lung cancer sclc prophylactic cranial irradiation pci fractional anisotropy fa}, doi={10.4108/icst.mobihealth.2014.257513} }- Sofia Benezi
Eustratios Karavasilis
Irene Karanasiou
George Matsopoulos
Eric Ventouras
Nikolaos Uzunoglu
Vasilios Kouloulias
Matilda Papathanasiou
Adreas Foteineas
Theodore Soldatos
Christin Iosif
Efstathios Efstathopoulos
Nikolaos Kelekis
Dimitrios Kelekis
Year: 2014
Tract-Based Spatial Statistics Analysis of Diffusion-Tensor Imaging Data in Patients with Small Cell Lung Cancer.
MOBIHEALTH
IEEE
DOI: 10.4108/icst.mobihealth.2014.257513
Abstract
Prophylactic cranial irradiation (PCI) is known to improve survival to a significant degree in Small Cell Lung Cancer (SCLC) patients. The aim of our study is to investigate changes in structural connectivity between healthy-volunteers and patients with SCLC, before and after PCI treatment. In this preliminary study we use diffusion tensor imaging (DTI) to identify changes in white matter structure in patient group pre radiotherapy to control group. The results have showed alterations in white matter structure. In the patient group lower fractional anisotropy (FA) and higher eigenvalues in white matter regions are observed compared to the control group. The results presented herein are subject to further investigation with larger patient and control groups.
