3d International ICST Conference on Bio-Inspired Models of Network, Information, and Computing Systems

Research Article

Molecular Communication on Artificial Cell Membranes

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  • @INPROCEEDINGS{10.4108/ICST.BIONETICS2008.4665,
        author={Jun-ichi Kikuchi and Masaru Mukai and Yoshihiro Sasaki and Satoshi Hiyama and Yuki Moritani and Tatsuya Suda},
        title={Molecular Communication on Artificial Cell Membranes},
        proceedings={3d International ICST Conference on Bio-Inspired Models of Network, Information, and Computing Systems},
        publisher={ICST},
        proceedings_a={BIONETICS},
        year={2010},
        month={5},
        keywords={Molecular communication Artificial Cell membrane Molecular switch Gemini peptide lipid Enzymatic reaction},
        doi={10.4108/ICST.BIONETICS2008.4665}
    }
    
  • Jun-ichi Kikuchi
    Masaru Mukai
    Yoshihiro Sasaki
    Satoshi Hiyama
    Yuki Moritani
    Tatsuya Suda
    Year: 2010
    Molecular Communication on Artificial Cell Membranes
    BIONETICS
    ICST
    DOI: 10.4108/ICST.BIONETICS2008.4665
Jun-ichi Kikuchi1,*, Masaru Mukai2,*, Yoshihiro Sasaki3,*, Satoshi Hiyama4,*, Yuki Moritani4,*, Tatsuya Suda5,*
  • 1: Graduate School of Materials Science, Nara Institute of Science and Technology Takayama, Ikoma, Nara 630-0192, Japan +81-743-72-6090
  • 2: Graduate School of Materials Science, Nara Institute of Science and Technology Takayama, Ikoma, Nara 630-0192, Japan +81-743-72-6093
  • 3: Institute of Biomaterials and Bioengineering, Tokyo Medical and Dental University Kanda-Surugadai, Chiyoda, Tokyo 101-0062, Japan +81-3-5280-8026
  • 4: Research Laboratories, NTT DOCOMO, Inc. Hikarino-oka, Yokosuka, Kanagawa 239-8536, Japan +81-46-840-3811
  • 5: School of Information and Computer Science, University of California, Irvine Irvine, CA 92697-3425, USA +1-949-824-5474
*Contact email: jkikuchi@ms.naist.jp, m-masaru@ms.naist.jp, ysasaki.org@tmd.ac.jp, hiyama@nttdocomo.co.jp, moritani@nttdocomo.co.jp, suda@ics.uci.edu

Abstract

Molecular communication is a bio-inspired communication paradigm using molecules as information carriers. In this paper, we built an example molecular communication system in aqueous media, which includes propagation of molecular capsules capable of carrying molecular information between a molecular sender and a molecular receiver and followed amplification of the information at the receiver. A gemini peptide lipid as a molecular switch embedded in the lipid bilayer membranes logically controlled propagation of molecular capsules formed with small liposomes from a sender to a receiver each composed of a giant liposome, with input signals, such as chemical, photonic, and thermal signals. In addition, the molecular switch acted as an artificial receptor at the receiver, receiving a photonic signal to communicate with an enzyme as a signal amplifier by using Cu2+ ion as a mediator between the receptor and the amplifier.