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Research Article

Alzheimer’s Disease Detection in MRI images using Deep Convolutional Neural Network Model

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  • @ARTICLE{10.4108/eetpht.10.6435,
        author={S. Naganandhini and P. Shanmugavadivu},
        title={ Alzheimer’s Disease Detection in MRI images using Deep Convolutional Neural Network Model},
        journal={EAI Endorsed Transactions on Pervasive Health and Technology},
        volume={10},
        number={1},
        publisher={EAI},
        journal_a={PHAT},
        year={2024},
        month={12},
        keywords={Alzheimer’s disease detection, MIRIAD datasets, Confusion Matrix, CNN architecture, ReLu, Dropout, Normal and Abnormal MRI images},
        doi={10.4108/eetpht.10.6435}
    }
    
  • S. Naganandhini
    P. Shanmugavadivu
    Year: 2024
    Alzheimer’s Disease Detection in MRI images using Deep Convolutional Neural Network Model
    PHAT
    EAI
    DOI: 10.4108/eetpht.10.6435
S. Naganandhini1, P. Shanmugavadivu2,*
  • 1: Arulmigu Palaniandavar Arts and Science College For Women
  • 2: Gandhigram Rural Institute
*Contact email: psvadivu67@gmail.com

Abstract

Alzheimer's disease (AD) is a neurodegenerative disease that affects cognitive abilities (thinking and memory etc) primarily among the elderly, due to which collective cognitive skills deteriorate, ultimately leading to death. Early detection of Alzheimer's disease is crucial for determining appropriate therapeutic options. This research investigates the use of a Deep Convolutional Neural Network (CNN) for detecting Alzheimer's disease. Due to similar brain patterns and pixel intensities, CNN demonstrates promising results in diagnosing AD through automated feature extraction and characterization. Deep Learning algorithms are designed to perform automated feature extraction and categorization of input image datasets. In this study, a two-way classifier categorizes each image as either Healthy Control (HC) or Alzheimer's disease (AD). Experiments were carried out with the MIRIAD dataset, and the accuracy of disease classification into binary categories was evaluated. The recorded results of CNN with 4- and 5 -layer architectures confirms the effectiveness of the proposed method for AD detection.

Keywords
Alzheimer’s disease detection, MIRIAD datasets, Confusion Matrix, CNN architecture, ReLu, Dropout, Normal and Abnormal MRI images
Received
2024-12-04
Accepted
2024-12-04
Published
2024-12-04
Publisher
EAI
http://dx.doi.org/10.4108/eetpht.10.6435

Copyright © 2024 Naganandhini et al., licensed to EAI. This is an open access article distributed under the terms of the CC BY-NCSA 4.0, which permits copying, redistributing, remixing, transformation, and building upon the material in any medium so long as the original work is properly cited.

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