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Research Article

Prediction of Paediatric Systemic Lupus Erythematosus Patients Using Machine Learning

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  • @ARTICLE{10.4108/eetpht.10.6386,
        author={Raja Rajeswari Ponnusamy and Lim Chun Cheak and Elaine Chan Wan Ling and Lim Sern Chin},
        title={Prediction of Paediatric Systemic Lupus Erythematosus Patients Using Machine Learning},
        journal={EAI Endorsed Transactions on Pervasive Health and Technology},
        volume={10},
        number={1},
        publisher={EAI},
        journal_a={PHAT},
        year={2024},
        month={12},
        keywords={Neural Network, Support Vector Machine, PLSE},
        doi={10.4108/eetpht.10.6386}
    }
    
  • Raja Rajeswari Ponnusamy
    Lim Chun Cheak
    Elaine Chan Wan Ling
    Lim Sern Chin
    Year: 2024
    Prediction of Paediatric Systemic Lupus Erythematosus Patients Using Machine Learning
    PHAT
    EAI
    DOI: 10.4108/eetpht.10.6386
Raja Rajeswari Ponnusamy1,*, Lim Chun Cheak1, Elaine Chan Wan Ling2, Lim Sern Chin3
  • 1: Asia Pacific University of Technology & Innovation
  • 2: International Medical University
  • 3: Universiti Teknologi MARA
*Contact email: raja.rajeswari@apu.edu.my

Abstract

Paediatric systemic lupus erythematosus (pSLE) is an autoimmune disease where the body's immune system attacks its own tissues, leading to organ damage. Advances in medical technology and the integration of artificial intelligence have significantly reduced the mortality rate of pSLE patients and improved their quality of life. Various studies have explored the link between environmental pollution and pSLE, utilizing machine learning to identify common gene expressions associated with the disease. However, the application of machine learning, particularly neural networks, to predict the status of pSLE patients over different timeframes remains underexplored. This study aims to demonstrate the effectiveness of  support vector machines (SVMs) and neural networks in predicting the status of pSLE patients. Results show that without SMOTE balancing, both SVMs and neural networks achieved an accuracy of 68.09%, while neural networks achieved the highest accuracy of 77.78% after SMOTE balancing. Healthcare stakeholders can employ these machine learning techniques to provide early insights into patients' future health status based on their current condition, thereby improving patient outcomes.

Keywords
Neural Network, Support Vector Machine, PLSE
Received
2024-12-04
Accepted
2024-12-04
Published
2024-12-04
Publisher
EAI
http://dx.doi.org/10.4108/eetpht.10.6386

Copyright © 2024 Ponnusamy et al., licensed to EAI. This is an open access article distributed under the terms of the CC BY-NC-SA 4.0, which permits copying, redistributing, remixing, transformation, and building upon the material in any medium so long as the original work is properly cited.

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