Research Article
Antiobesity Properties of Star Fruits Extract and its Combination with Toddalia Aculeata Leaves Extract
@INPROCEEDINGS{10.4108/eai.3-6-2021.2310747, author={Isti Sundari and Dono Indarto and Paramasari Dirgahayu}, title={Antiobesity Properties of Star Fruits Extract and its Combination with Toddalia Aculeata Leaves Extract }, proceedings={Proceedings of the 1st International Conference on Education, Humanities, Health and Agriculture, ICEHHA 2021, 3-4 June 2021, Ruteng, Flores, Indonesia}, publisher={EAI}, proceedings_a={ICEHHA}, year={2021}, month={8}, keywords={star fruits; t aculeata; obesity}, doi={10.4108/eai.3-6-2021.2310747} }- Isti Sundari
Dono Indarto
Paramasari Dirgahayu
Year: 2021
Antiobesity Properties of Star Fruits Extract and its Combination with Toddalia Aculeata Leaves Extract
ICEHHA
EAI
DOI: 10.4108/eai.3-6-2021.2310747
Abstract
The existing pharmacological therapy of obesity often causes side effects. Therefore, this study aimed to explore active compounds derived from star fruits and Toddallia acuelata leaves extracts for development of obesity therapy. From phytochemical screening test, it was found that star fruits extract (SFE) contained alkaloids, phenolics, and flavonoids while T. acuelata leaves extract (TLE) contained alkaloids, phenolics, saponins, and steroids. Based on the in-silico study confirmed with a chemical analysis using the Liquid Chromatography-Mass Spectrometry (LC-MS) technique, SFE contained Epicathecine Gallate (tannin derivative). Furthermore, the highest antioxidant activity was detected in pure TLE (58.5%) followed by combination of 25: 75% SFE and TLE (46.81%). In conclusion, TLE and combination of 25:75% star fruits and T. acuelata extracts become a potential obesity therapy. Further research is required for the investigation of pharmacological properties of those extracts.