Proceedings of the 1st International Conference on Education, Humanities, Health and Agriculture, ICEHHA 2021, 3-4 June 2021, Ruteng, Flores, Indonesia

Research Article

Livestock-Associated Methicillin-Resistant Staphylococcus Aureus (LA-MRSA) CC398: An Emerging Infectious Disease

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  • @INPROCEEDINGS{10.4108/eai.3-6-2021.2310716,
        author={Aswin Rafif Khairullah and Sri Agus Sudjarwo and Mustofa Helmi Effendi and Sancaka Cashyer Ramandinianto and Katty Hendriana Priscilia Riwu},
        title={Livestock-Associated Methicillin-Resistant Staphylococcus Aureus (LA-MRSA) CC398: An Emerging Infectious Disease },
        proceedings={Proceedings of the 1st International Conference on Education, Humanities, Health and Agriculture, ICEHHA 2021, 3-4 June 2021, Ruteng, Flores, Indonesia},
        publisher={EAI},
        proceedings_a={ICEHHA},
        year={2021},
        month={8},
        keywords={la-mrsa; cc398; emerging infectious disease},
        doi={10.4108/eai.3-6-2021.2310716}
    }
    
  • Aswin Rafif Khairullah
    Sri Agus Sudjarwo
    Mustofa Helmi Effendi
    Sancaka Cashyer Ramandinianto
    Katty Hendriana Priscilia Riwu
    Year: 2021
    Livestock-Associated Methicillin-Resistant Staphylococcus Aureus (LA-MRSA) CC398: An Emerging Infectious Disease
    ICEHHA
    EAI
    DOI: 10.4108/eai.3-6-2021.2310716
Aswin Rafif Khairullah1,*, Sri Agus Sudjarwo2, Mustofa Helmi Effendi3, Sancaka Cashyer Ramandinianto4, Katty Hendriana Priscilia Riwu5
  • 1: Doctoral Program in Veterinary Science, Faculty of Veterinary Medicine, Universitas Airlangga, Surabaya, Indonesia
  • 2: Department of Veterinary Pharmacology, Faculty of Veterinary Medicine, Universitas Airlangga, Surabaya, Indonesia
  • 3: Department of Veterinary Public Health, Faculty of Veterinary Medicine, Universitas Airlangga, Surabaya, Indonesia
  • 4: Master Program in Veterinary Disease and Public Health, Faculty of Veterinary Medicine, Universitas Airlangga, Surabaya, Indonesia
  • 5: Universitas Airlangga, Surabaya, Indonesia3 Master Program in Veterinary Disease and Public Health, Faculty of Veterinary Medicine, Universitas Airlangga, Surabaya, Indonesia
*Contact email: aswinrafif@gmail.com

Abstract

Livestock-associated methicillin-resistant Staphylococcus aureus (LA-MRSA) is a pathogenic bacterial strain that can infect livestock, pets and humans. LA-MRSA was identified for the first time in 2005 where the new MRSA clone of sequence type 398 (ST398) was grouped and identified in the clone complex 398 (CC398). Cases of LA-MRSA CC398 infection began to be reported frequently in the next few years. From 2000 onwards, case reports of LA-MRSA CC398 infection are becoming more frequent. LA-MRSA CC398 transmission to the host is generally mediated by physical contact with livestock, but also through contaminated dust. LA-MRSA CC398 has the same virulence potential as Staphylococcus aureus found in humans and is generally associated with the same clinical features. Rapid detection of LA-MRSA examination can be done with a nasal swab, it is very important to adequately identify individuals who have been infected with LA-MRSA and molecular detection of LA-MRSA CC398 using polymerase chain reaction (PCR). Several other antibiotics such as linezolid, telavancin, daptomycin, tedizoid, dalbavancin, oritavancin, ceftobiprole, and ceftaroline have been developed and approved for the treatment of the LA-MRSA CC398 infection. Interventions that need to be done to prevent transmission and infection of LA-MRSA CC398 include screening, isolation of contacts, hand hygiene, cohorts, and decolonization as additional standard precautions.