Proceedings of the 3rd Sriwijaya International Conference on Basic and Applied Sciences, SICBAS 2023, November 3, 2023, Palembang, Indonesia

Research Article

An Ethanolic Extract of Psidium guajava L. as Media for Biosynthesis of ZnO-CuO Nanoparticles: Characterization and In Vitro Study to Staphylococcus aureus Bacteria

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  • @INPROCEEDINGS{10.4108/eai.3-11-2023.2347961,
        author={Ahmad  Fatoni and Khoirunnisa  Sari and Lasmaryna  Sirumapea and Nurlisa  Hidayati},
        title={An Ethanolic Extract of Psidium guajava L. as Media for Biosynthesis of ZnO-CuO Nanoparticles: Characterization and In Vitro Study to Staphylococcus aureus Bacteria},
        proceedings={Proceedings of the 3rd Sriwijaya International Conference on Basic and Applied Sciences, SICBAS 2023, November 3, 2023, Palembang, Indonesia},
        publisher={EAI},
        proceedings_a={SICBAS},
        year={2024},
        month={8},
        keywords={zno-cuo nanoparticles characterization antibacterial staphylococcus aureus},
        doi={10.4108/eai.3-11-2023.2347961}
    }
    
  • Ahmad Fatoni
    Khoirunnisa Sari
    Lasmaryna Sirumapea
    Nurlisa Hidayati
    Year: 2024
    An Ethanolic Extract of Psidium guajava L. as Media for Biosynthesis of ZnO-CuO Nanoparticles: Characterization and In Vitro Study to Staphylococcus aureus Bacteria
    SICBAS
    EAI
    DOI: 10.4108/eai.3-11-2023.2347961
Ahmad Fatoni1,*, Khoirunnisa Sari1, Lasmaryna Sirumapea1, Nurlisa Hidayati2
  • 1: Pharmaceutical Chemistry, Bhakti Pertiwi College of Pharmaceutical Sciences
  • 2: Department of Chemistry, Faculty of Mathematic and Natural Sciences, Sriwijaya University
*Contact email: tonistifibp@gmail.com

Abstract

ZnO and CuO nanoparticles have attracted a lot of attention lately because of their special qualities. In terms of structure and characteristics, this group of nanostructures is the most preferred one. The research was done on biosynthesis ZnO-CuO nanoparticle. The objective of this study was to synthesize ZnO-CuO nanoparticles, characterize them, and use them as an antibacterial agent against Staphylococcus aureus. The media of ethanolic extract of Psidium guajava L. in alkaline solution were used to biosynthesize ZnO-CuO nanoparticles. The tools used to examine the functional groups and physical structure of ZnO-CuO nanoparticles include FTIR spectroscopy and X-ray diffraction. Using the well agar diffusion method, ZnO-CuO nanoparticle suspension was used as an antibacterial agent. Wavenumbers of the functional groups of Zn-O and Cu-O groups are 507.28 and 617.22 cm-1, respectively. ZnO-CuO nanoparticles' crystallite size was calculated to be 2.33 nm. Staphylococcus aureus may be resistant to the ZnO/CuO nanoparticles' antimicrobial effects. ZnO-CuO nanoparticles have a greater inhibitory zone than ZnO or CuO nanoparticles.