Estimation of Urea and Creatinine in Type 2 Diabetes Mellitus Patients

The disease of Type-2 DM rapidly had become a problem of health globally due to a fast-growing and aged population, urbanisation and increasing obesity prevalence due to decreasing physical activity. The case of diabetic-nephropathy is concerned with the most important reasons for chronic kidney failure. For assessing kidney function, all of the serum urea, as well as creatinine, are mostly used. The present study was carried out to detect the impairment of kidney function in patients of type 2 DM compared with healthy non -diabetic control subjects. To detect the inefficient kidney function in diabetics in General Musul Hospital, Musul, Iraq,. The biochemical parameters had been determined by the use of a full automatic clinical chemistry analyzer. Study findings clarified that in regard of urea in blood although the difference was insignificant, the blood urea level was higher in patients of type 2 DM in comparison with non -diabetics for both female and male. A high significant difference was present regarding serum creatinine between diabetics and controls. There were 5 diabetics with elevated urea yet only 1 subject among the controls. The biochemical parameters of both blood urea and creatinine are good markers to assess kidney functions.