Proceedings of the 1st International Multi-Disciplinary Conference Theme: Sustainable Development and Smart Planning, IMDC-SDSP 2020, Cyperspace, 28-30 June 2020

Research Article

Incidence of Hepatitis C Infection among Multi-transfused β- thalassemia Major Patients and its Correlation to Blood Groups in Amara City

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  • @INPROCEEDINGS{10.4108/eai.28-6-2020.2298223,
        author={Younus  Abdullah and Nidhal  Hashim and Safaa  Sultan},
        title={Incidence of Hepatitis C Infection among Multi-transfused β- thalassemia Major Patients and its Correlation to Blood Groups in Amara City},
        proceedings={Proceedings of the 1st International Multi-Disciplinary Conference Theme: Sustainable Development and Smart Planning, IMDC-SDSP 2020, Cyperspace, 28-30 June 2020},
        publisher={EAI},
        proceedings_a={IMDC-SDSP},
        year={2020},
        month={9},
        keywords={hcv thalassemia correlation blood group},
        doi={10.4108/eai.28-6-2020.2298223}
    }
    
  • Younus Abdullah
    Nidhal Hashim
    Safaa Sultan
    Year: 2020
    Incidence of Hepatitis C Infection among Multi-transfused β- thalassemia Major Patients and its Correlation to Blood Groups in Amara City
    IMDC-SDSP
    EAI
    DOI: 10.4108/eai.28-6-2020.2298223
Younus Abdullah1,*, Nidhal Hashim1, Safaa Sultan2
  • 1: Southern Technical University, Amara Technical Institute. Amara city. Iraq
  • 2: Northern Technical University, Mosul Medical Institute. Mosul city. Iraq
*Contact email: younusjasim@stu.edu.iq

Abstract

. Multi-transfused β- thalassemia major patients still at high risk of acquiring blood-borne viruses just like hepatitis C (HCV), hepatitis B (HBV) and human immunodeficiency virus (HIV). To estimate the percent of HCV infection among multi-transfused β- thalassemia major patients, a sample of (109) β- thalassemia major patients were subjected to anti-HCV screening test using enzyme-linked fluorescent assay (ELFA) technique. The results revealed that 30 (27.5%) patients present + anti-HCV in Amara city. However, the infection rate was higher in the male gender than females and increased with age. The results also found that HCV infection is predominant in B+, O+, and A+ blood groups, moreover, a highly significant positive correlation detected between HCV infection and B+ blood group. The study concluded that there is an elevated rate of HCV infection among β- thalassemia major patients, requiring more efficient viral screening techniques to the blood donors, the positive relationship between blood group and HCV infection suggests a role of gene-environment interaction and needing molecular studies to clarify such correlation.