Proceedings of the 1st International Multi-Disciplinary Conference Theme: Sustainable Development and Smart Planning, IMDC-SDSP 2020, Cyperspace, 28-30 June 2020

Research Article

New Cu (II)and Zn (II) complexes with O- nitrobenzylidene trimethoprim , Evaluation of their Antibacterial activities

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  • @INPROCEEDINGS{10.4108/eai.28-6-2020.2298121,
        author={Rana  Abed and Fadia  Ahmed and Samaa  Raoof},
        title={New Cu (II)and Zn (II) complexes with O- nitrobenzylidene trimethoprim , Evaluation of their Antibacterial activities},
        proceedings={Proceedings of the 1st International Multi-Disciplinary Conference Theme: Sustainable Development and Smart Planning, IMDC-SDSP 2020, Cyperspace, 28-30 June 2020},
        publisher={EAI},
        proceedings_a={IMDC-SDSP},
        year={2020},
        month={9},
        keywords={o- nitrobenzylidenetrimethoprim trimethoprim cu\& zn complexes antibactial activity},
        doi={10.4108/eai.28-6-2020.2298121}
    }
    
  • Rana Abed
    Fadia Ahmed
    Samaa Raoof
    Year: 2020
    New Cu (II)and Zn (II) complexes with O- nitrobenzylidene trimethoprim , Evaluation of their Antibacterial activities
    IMDC-SDSP
    EAI
    DOI: 10.4108/eai.28-6-2020.2298121
Rana Abed1,*, Fadia Ahmed1, Samaa Raoof2
  • 1: University of Mosul
  • 2: Northern Technical University, Mosul Technical Institute
*Contact email: ranaalbustani@uomosul.edu.iq

Abstract

Copper (II) and Zinc (II)Complexes with O- nitrobenzylidenetrimethoprim were prepared. The complexes were identified by employing Technique of CHNS analysis , molar conductance, magnetic susceptibities and spectral measurements (FT-IR electronic spectra , 1H NMR , 13C-NMR), The above ligand formed ionic complexes having general formulae [M (ONBTMP)2 ]X2 in neutral medium and [ M (ONBTMP-H) 2 ] in basic medium , M=Cu, Zn, X=Cl, NO3, SO4, CH3COO, ONBTMP = ortho-nitrobenzylidenetrimethoprim, hexa coordinated mononuclear, complexes were investigated by this study and having distorted octahedral geometries in Copper complexes and octahedral geometries in Zinc complexes Then the antibacterial activity has been studied for both of ligand and all complexes by using agar plate diffusion techniques against "Pathogenic Bacterial strains {Staphylococcus aureus, pseudomonas aeruginosa, Proteus mirabilis , Escherichia coli and Bacillus subtilis }" [18]. Both of ligand and complexes were found to have antibactial activity, Beter than of the primary article Trimethoprim.