Research Article
New Cu (II)and Zn (II) complexes with O- nitrobenzylidene trimethoprim , Evaluation of their Antibacterial activities
@INPROCEEDINGS{10.4108/eai.28-6-2020.2298121, author={Rana Abed and Fadia Ahmed and Samaa Raoof}, title={New Cu (II)and Zn (II) complexes with O- nitrobenzylidene trimethoprim , Evaluation of their Antibacterial activities}, proceedings={Proceedings of the 1st International Multi-Disciplinary Conference Theme: Sustainable Development and Smart Planning, IMDC-SDSP 2020, Cyperspace, 28-30 June 2020}, publisher={EAI}, proceedings_a={IMDC-SDSP}, year={2020}, month={9}, keywords={o- nitrobenzylidenetrimethoprim trimethoprim cu\& zn complexes antibactial activity}, doi={10.4108/eai.28-6-2020.2298121} }- Rana Abed
Fadia Ahmed
Samaa Raoof
Year: 2020
New Cu (II)and Zn (II) complexes with O- nitrobenzylidene trimethoprim , Evaluation of their Antibacterial activities
IMDC-SDSP
EAI
DOI: 10.4108/eai.28-6-2020.2298121
Abstract
Copper (II) and Zinc (II)Complexes with O- nitrobenzylidenetrimethoprim were prepared. The complexes were identified by employing Technique of CHNS analysis , molar conductance, magnetic susceptibities and spectral measurements (FT-IR electronic spectra , 1H NMR , 13C-NMR), The above ligand formed ionic complexes having general formulae [M (ONBTMP)2 ]X2 in neutral medium and [ M (ONBTMP-H) 2 ] in basic medium , M=Cu, Zn, X=Cl, NO3, SO4, CH3COO, ONBTMP = ortho-nitrobenzylidenetrimethoprim, hexa coordinated mononuclear, complexes were investigated by this study and having distorted octahedral geometries in Copper complexes and octahedral geometries in Zinc complexes Then the antibacterial activity has been studied for both of ligand and all complexes by using agar plate diffusion techniques against "Pathogenic Bacterial strains {Staphylococcus aureus, pseudomonas aeruginosa, Proteus mirabilis , Escherichia coli and Bacillus subtilis }" [18]. Both of ligand and complexes were found to have antibactial activity, Beter than of the primary article Trimethoprim.
