Research Article
Effect Differences of Fermented and Non-Fermented Red Dragon Fruit Peel on Blood Glucose Levels of Hypercholestrolemic Wistar Rats
@INPROCEEDINGS{10.4108/eai.28-4-2021.2312240, author={Natalia Desy Putriningtyas and Mardiana Mardiana and Siti Wahyuningsih}, title={Effect Differences of Fermented and Non-Fermented Red Dragon Fruit Peel on Blood Glucose Levels of Hypercholestrolemic Wistar Rats}, proceedings={Proceedings of the 5th International Conference on Sports, Health, and Physical Education, ISMINA 2021, 28-29 April 2021, Semarang, Central Java, Indonesia}, publisher={EAI}, proceedings_a={ISMINA}, year={2021}, month={10}, keywords={blood glucose level marmalade red dragon fruit peel wistar yogurt}, doi={10.4108/eai.28-4-2021.2312240} }
- Natalia Desy Putriningtyas
Mardiana Mardiana
Siti Wahyuningsih
Year: 2021
Effect Differences of Fermented and Non-Fermented Red Dragon Fruit Peel on Blood Glucose Levels of Hypercholestrolemic Wistar Rats
ISMINA
EAI
DOI: 10.4108/eai.28-4-2021.2312240
Abstract
Hypercholesterolemia is associated with oxidative stress. Antioxidant activity can found in red dragon fruit peel. This study aims to analyse the effect of fermented and non-fermented red dragon fruit peel on blood glucose levels of hypercholesterolemic Wistar rats. Twenty plasma Wistar rats were divided into four groups: P1 (negative); P2 (hypercholesterolemic group, not received any treatment); P3 (red dragon fruit peel yogurt 1.8g/200g BW); P4 (red dragon fruit peel marmalade 0.94g/200g BW). Hypercholesterolemic condition was induced using cholesterol and cholic acid powder. Blood glucose levels were measured using GOD-PAP. The paired t-test and One-Way ANOVA was used to determine the mean differences in blood glucose level before and after intervention. The reduction in blood glucose levels in P1; P2; P3 and P4 were 0.28 ±0.55 mg/dL; 2.66 ±1.92 mg/dL; -24.60 ±5.77 mg/dL; -18.66 ±2.23 mg/dL, respectively. We concluded that red dragon fruit peel yogurt lowers blood glucose more than dragon fruit peel marmalade.