Research Article
Biomarkers of Oxidative Stress for Human Health: Experiment of Different Swimming Exercise on Male Wistar Rats
@INPROCEEDINGS{10.4108/eai.28-4-2021.2312212, author={Agus Hariyanto and Anindya Mar’atus Sholikhah and Yetty Septiani Mustar}, title={Biomarkers of Oxidative Stress for Human Health: Experiment of Different Swimming Exercise on Male Wistar Rats}, proceedings={Proceedings of the 5th International Conference on Sports, Health, and Physical Education, ISMINA 2021, 28-29 April 2021, Semarang, Central Java, Indonesia}, publisher={EAI}, proceedings_a={ISMINA}, year={2021}, month={10}, keywords={exercise free radical intensity malondialdehyde oxidative stress superoxide dismutase}, doi={10.4108/eai.28-4-2021.2312212} }- Agus Hariyanto
Anindya Mar’atus Sholikhah
Yetty Septiani Mustar
Year: 2021
Biomarkers of Oxidative Stress for Human Health: Experiment of Different Swimming Exercise on Male Wistar Rats
ISMINA
EAI
DOI: 10.4108/eai.28-4-2021.2312212
Abstract
This study aims to compare the biomarker of oxidative stress in rats after subjected to exercise in different intensity. It was an experimental study involving 15 male Wistar rats. Rats were allocated to control (C), moderate swimming training (M) and exhaustive swimming training (EX). Rats in M group were forced to swim twice a week for 15 minutes, while rats in EX were forced to swim with external load added (5% of bodyweight) until exhausted or once rats stayed submerge for 10 s. After two weeks of exercise, rats were euthanized and 4 mL of blood samples were drawn to measure MDA and SOD. The results of this study revealed a significant difference in MDA and SOD level between groups. Rats in EX were found to have highest level of MDA (38.10 ± 2.29) as well as lowest in SOD level (1.06 ± 0.06) than the peers in M. The findings indicate that moderate exercise is the most suitable exercise to prevent oxidative stress.