Proceedings of the 1st International Conference on Health Science, ICHS 2020, 26-27 October 2020, Jakarta, Indonesia

Research Article

A retrospective study of the Antibiotics Prophylactic Use in Appendectomy Patient with ATC/DDD and DU 90% Method in Regional General Hospital in Jakarta

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  • @INPROCEEDINGS{10.4108/eai.26-10-2020.2311323,
        author={Azrifitria  Azrifitria and Harfia  Mudahar and Nurul  Fazriyah},
        title={A retrospective study of the Antibiotics Prophylactic Use in Appendectomy Patient with ATC/DDD and DU 90\% Method in Regional General Hospital in Jakarta},
        proceedings={Proceedings of the 1st International Conference on Health Science, ICHS 2020, 26-27 October 2020, Jakarta, Indonesia},
        publisher={EAI},
        proceedings_a={ICHS},
        year={2021},
        month={8},
        keywords={prophylactic antibiotic appendectomy atcc/ddd},
        doi={10.4108/eai.26-10-2020.2311323}
    }
    
  • Azrifitria Azrifitria
    Harfia Mudahar
    Nurul Fazriyah
    Year: 2021
    A retrospective study of the Antibiotics Prophylactic Use in Appendectomy Patient with ATC/DDD and DU 90% Method in Regional General Hospital in Jakarta
    ICHS
    EAI
    DOI: 10.4108/eai.26-10-2020.2311323
Azrifitria Azrifitria1,*, Harfia Mudahar2, Nurul Fazriyah1
  • 1: Pharmacy Study Program, Faculty of Health Sciences UIN Syarif Hidayatullah Jakarta, Ciputat, 15419. Indonesia
  • 2: Department of pharmacy, Regional general hospital Cengkareng, West Jakarta
*Contact email: azrifitria@uinjkt.ac.id

Abstract

Appendicitis is the most common cause of acute abdomen which requires surgical treatment to prevent worse complications. Inappropriate use of prophylactic antibiotic is one of the triggers surgical site infection. This retrospective study aimed to determine the quantitative analysis of antibiotics prophylactic use according to the anatomical therapeutics chemical classification/defined daily dose (ATCC/DDD) methodology. This research was conducted using cross sectional design with retrospective data collection during January to December 2016 at regional general hospital in Jakarta and data were analyzed using the DDD method and drug utilization (DU) 90%. A total of 119 total patients included as samples in this study. The results showed that the ceftriaxone was prophylactic antibiotic with highest DDD was 46.52 /100 patient-days. Prophylactic antibiotics included in DU 90% segment were ceftriaxone and metronidazole. These study underline the need for antibiotic stewardship to improve the quality of antibiotic use.