Proceedings of the 1st International Conference on Health Science, ICHS 2020, 26-27 October 2020, Jakarta, Indonesia

Research Article

Antibacterial evaluation of Spray Gel Formula of Angsana Leaf Extract (Pterocarpus indicus Willd.) Using Combination Base of Carbopol 940 and HPMC

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  • @INPROCEEDINGS{10.4108/eai.26-10-2020.2311310,
        author={Nelly Suryani and Vivi Anggia and Afifah Amatullah},
        title={Antibacterial evaluation of Spray Gel Formula of Angsana Leaf Extract (Pterocarpus indicus Willd.) Using Combination Base of Carbopol 940 and HPMC},
        proceedings={Proceedings of the 1st International Conference on Health Science, ICHS 2020, 26-27 October 2020, Jakarta, Indonesia},
        publisher={EAI},
        proceedings_a={ICHS},
        year={2021},
        month={8},
        keywords={angsana leaves spray gel staphylococcus aureus pterocarpus indicus willd},
        doi={10.4108/eai.26-10-2020.2311310}
    }
    
  • Nelly Suryani
    Vivi Anggia
    Afifah Amatullah
    Year: 2021
    Antibacterial evaluation of Spray Gel Formula of Angsana Leaf Extract (Pterocarpus indicus Willd.) Using Combination Base of Carbopol 940 and HPMC
    ICHS
    EAI
    DOI: 10.4108/eai.26-10-2020.2311310
Nelly Suryani1, Vivi Anggia1,*, Afifah Amatullah1
  • 1: Pharmacy Study Program, Faculty of Health Sciences UIN Syarif Hidayatullah Jakarta, Ciputat, 15419. Indonesia
*Contact email: vivi.anggia@uinjkt.ac.id

Abstract

Angsana leaves ethanol extracts known to provide antibacterial activity. The aim of this study was to determine the inhibitory activity produced by spray gel using a combination base of carbopol 940 and HPMC against Staphylococcus aureus as one of the bacteria causes of skin infections. Three formulas were prepared with various base concentrations then tested for its antibacterial activity by disc diffusion method. On initial study showed that concentration of 30% angsana leaves extract gave best inhibition so it was used in formula. The base concentration at F1 was 0.4% carbopol 940 and 0.4% HPMC, F2 was 0.2% carbopol 940 and 0.4% HPMC and F3 was 0.4% carbopol at 10.5, 11mm, and 11mm. The combination of gelling agent used in the formula did not show a significant difference in antibacterial activity, but the formula needs to be studied further to evaluate its performance.