amsys 18(17): e5

Research Article

Heart Disease Diagnosis Based on Deep Radial Basis Function Kernel Machine

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  • @ARTICLE{10.4108/eai.23-3-2018.154774,
        author={Mashail Alsalamah and Saad Amin and Vasile Palade},
        title={Heart Disease Diagnosis Based on Deep Radial Basis Function Kernel Machine},
        journal={EAI Endorsed Transactions on Ambient Systems},
        keywords={machine Learning, Classification, Unsupervised Regression, Supervised Regression, Principal Component Analysis},
  • Mashail Alsalamah
    Saad Amin
    Vasile Palade
    Year: 2018
    Heart Disease Diagnosis Based on Deep Radial Basis Function Kernel Machine
    DOI: 10.4108/eai.23-3-2018.154774
Mashail Alsalamah,*, Saad Amin, Vasile Palade
    *Contact email:


    Over the years Radial Basis Function (RBF) Kernel Machines have been used in Machine Learning tasks, but there are certain flaws that prevent their usage in some up-to-date applications (e.g., some Kernel Machines suffer from fast growth number of learning parameters whilst predicting data with large number of variations). Besides, Kernel Machines with single hidden layer have no mechanisms for features selection in multidimensional data space, and machine-learning task becomes intractable with enlargement of the data available for analysis. To address these issues, this paper investigates the usage of a framework for “deep learning” architecture composed of multilayered adaptive non-linear components – Multilayer RBF Kernel Machine. To be precise, three different approaches of features selection and dimensionality reduction to train RBF based on Multilayer Kernel Learning are explored, and comparisons between them in terms of accuracy, performance and computational complexity are made. As opposed to the “shallow learning” algorithm with usually single layer architecture, results show that the multilayered system produces better results with large and highly varied data. In particular, features selection and dimensionality reduction, as a class of the multilayer method, shows results that are more accurate. This paper proposes a novel scheme based on deep Multilayer RBF Kernel Machine learning for sleep apnea detection and quantification using statistical features of ECG signals. The results obtained show that the newly proposed approach provides significant accuracy improvements compared to state-of-the-art methods. Because of its noninvasive and low-cost nature, this algorithm has the potential for numerous applications in sleep medicine.