Proceedings of the First National Seminar Universitas Sari Mulia, NS-UNISM 2019, 23rd November 2019, Banjarmasin, South Kalimantan, Indonesia

Research Article

A Review: Protease Inhibitors From Sponge Jaspis Sp. Associated Bacteria

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  • @INPROCEEDINGS{10.4108/eai.23-11-2019.2298399,
        author={Dede  Mahdiyah and Bayu Hari Mukti},
        title={A Review: Protease Inhibitors From Sponge Jaspis Sp. Associated Bacteria},
        proceedings={Proceedings of the First National Seminar Universitas Sari Mulia, NS-UNISM 2019,  23rd November 2019, Banjarmasin, South Kalimantan, Indonesia},
        publisher={EAI},
        proceedings_a={NS-UNISM},
        year={2020},
        month={7},
        keywords={marine bacteria jaspis sp protease inhibitors},
        doi={10.4108/eai.23-11-2019.2298399}
    }
    
  • Dede Mahdiyah
    Bayu Hari Mukti
    Year: 2020
    A Review: Protease Inhibitors From Sponge Jaspis Sp. Associated Bacteria
    NS-UNISM
    EAI
    DOI: 10.4108/eai.23-11-2019.2298399
Dede Mahdiyah1,*, Bayu Hari Mukti2
  • 1: Department of Pharmacy, Faculty of Health, Universitas Sari Mulia, Banjarmasin, Indonesia
  • 2: Department of Educational Biology, STKIP PGRI Banjarmasin, Indonesia
*Contact email: mahdiyahdede@yahoo.co.id

Abstract

Protease inhibitors are enzymes that function to inactivate target proteases secreted by pathogenic bacteria to humans such as emphysema, pancreatic disease, arthritis, thrombosis, high blood pressure, cancer, and AIDS. The sponge is a good natural source for producing bioactive components including enzyme inhibitors. Jaspis sp is a genus from a sponge that has potential compounds as a protease inhibitor to combat Pseudomonas aeruginosa, Staphylococcus aureus, and EPEC K11. The interaction of sponges with bacteria occurs in the form of commensalism symbiosis that produces bioactive compounds that are important for human life.