Proceedings of the 13th International Interdisciplinary Studies Seminar, IISS 2019, 30-31 October 2019, Malang, Indonesia

Research Article

Effect of Iron, Aluminum and Zinc (as Anoda) on Metformin Deconcentration and Aspirin Deconcentration with Electrolysis Method

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  • @INPROCEEDINGS{10.4108/eai.23-10-2019.2293037,
        author={Suhartana  Suhartana and Purwanto  Purwanto and Adi  Darmawan},
        title={Effect of Iron, Aluminum and Zinc (as Anoda) on Metformin Deconcentration and Aspirin Deconcentration with Electrolysis Method},
        proceedings={Proceedings of the 13th International Interdisciplinary Studies Seminar, IISS 2019, 30-31 October 2019, Malang, Indonesia},
        publisher={EAI},
        proceedings_a={IISS},
        year={2020},
        month={3},
        keywords={aspirin metformin electrolysis nacl solution fenton reagents},
        doi={10.4108/eai.23-10-2019.2293037}
    }
    
  • Suhartana Suhartana
    Purwanto Purwanto
    Adi Darmawan
    Year: 2020
    Effect of Iron, Aluminum and Zinc (as Anoda) on Metformin Deconcentration and Aspirin Deconcentration with Electrolysis Method
    IISS
    EAI
    DOI: 10.4108/eai.23-10-2019.2293037
Suhartana Suhartana1,*, Purwanto Purwanto1, Adi Darmawan1
  • 1: Universitas Diponegoro, Indonesia
*Contact email: suhartana@live.undip.ac.id

Abstract

Aspirin and metformin are drugs that function as an analgesic-antiseptic, anti-inflammatory, and antiplatet. Ferrous metal, aluminum metal and zinc metal are easily found and often used by the public. This study aims to reduce the two drugs by electrolysis method, using three different metals, namely iron metal, aluminum metal and zinc metal as an anode. The success of the electrolysis process was seen with a decrease in the sample COD index. In situations without the addition of electrolytes using ferrous metals, aluminum metals and zinc metals the COD index decreases in the sample very low (10-15%). Interactions between drugs during electrolysis are tracked with possible changes in the chromophore group (with UV-Visible spectrum) and functional groups (with FTIR spectrum) of the sample. From the research data obtained information that there is a decrease and shift in the UV-Visible spectrum and changes in the functional group after the electrolysis process occurs. The electrolysis process of Metformin and Aspirin occurs optimally at a distance of 1 cM (in iron, aluminum and zinc as an anode and carbon as an anode) and a processing time of 30 minutes. The voltage used in the electrolysis process of Metformin is optimal at 3 volts and 9 volts in the Aspirin electrolysis process (in iron and aluminum as an anode and carbon as an anode). The best electrolysis percentage is obtained, after adding NaCl solution and Fenton's reagent in the range of 65 - 70%.