Proceedings of The 5th Annual International Seminar on Trends in Science and Science Education, AISTSSE 2018, 18-19 October 2018, Medan, Indonesia

Research Article

Factors Influence GLUT-4 Levels of Type 2 Diabetes Mellitus Patients in Medan City, Indonesia

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  • @INPROCEEDINGS{10.4108/eai.18-10-2018.2287358,
        author={Rina  Amelia and Novita Sari Harahap},
        title={Factors Influence GLUT-4 Levels of Type 2 Diabetes Mellitus Patients in Medan City, Indonesia},
        proceedings={Proceedings of The 5th Annual International Seminar on Trends in Science and Science Education, AISTSSE 2018, 18-19 October 2018, Medan, Indonesia},
        publisher={EAI},
        proceedings_a={AISTSSE},
        year={2019},
        month={10},
        keywords={glut4 physical activity obesity blood glucose level},
        doi={10.4108/eai.18-10-2018.2287358}
    }
    
  • Rina Amelia
    Novita Sari Harahap
    Year: 2019
    Factors Influence GLUT-4 Levels of Type 2 Diabetes Mellitus Patients in Medan City, Indonesia
    AISTSSE
    EAI
    DOI: 10.4108/eai.18-10-2018.2287358
Rina Amelia1,*, Novita Sari Harahap2
  • 1: Department of Community Medicine/Public Health, Faculty of Medicine, Universitas Sumatera Utara
  • 2: Faculty of Sport Sciences, State University of Medan
*Contact email: rina2@usu.ac.id

Abstract

The resistance of insulin in type 2 Diabetes mellitus patients (T2DM) will have a significant impact on glucose regulation with Glucose transporter-4 (GLUT-4) translocation. Glucose transporter-4 plays an essential role in the transport of glucose to most cells. The study design was analytic with a cross sectional approach. The study population was T2DM patient in Medan City with the number of people who have fulfilled the inclusion and exclusion criteria amount 83 patients. Data collection is done by interviewing and patient blood test. Assessment of physical activity of diabetic patients using a global questionnaire physical activity (GPAQ). GLUT-4 levels were assessed using Human Glut-4 with ELISA Method. The nutritional status and history of drug use by direct measurement and interviews. Data analysis using independent T-test with SPSS computer program. The results showed there was a relationship between physical activity and obesity with levels of GLUT-4 (p <0.05), and there was no relationship between consumption of drugs with levels of GLUT4 (p <0.05). By increasing physical activity, proper nutrition management and weight control will help improve insulin sensitivity so that it can control blood sugar levels in T2DM patients