Research Article
Effects of Giving Red Fruit Oil on Creatinine and Urea Levels of Rats (Rattus Novergicus) on Maximal Physical Activity
@INPROCEEDINGS{10.4108/eai.18-10-2018.2287348, author={Fajar Apollo Sinaga and Pangondian Hotliber Purba and Novita Sari Harahap and Rika Nailuvar Sinaga and Marsal Risfandi and Ramlan Silaban}, title={Effects of Giving Red Fruit Oil on Creatinine and Urea Levels of Rats (Rattus Novergicus) on Maximal Physical Activity}, proceedings={Proceedings of The 5th Annual International Seminar on Trends in Science and Science Education, AISTSSE 2018, 18-19 October 2018, Medan, Indonesia}, publisher={EAI}, proceedings_a={AISTSSE}, year={2019}, month={10}, keywords={red fruit oil creatinine urea maximal physical activity}, doi={10.4108/eai.18-10-2018.2287348} }- Fajar Apollo Sinaga
Pangondian Hotliber Purba
Novita Sari Harahap
Rika Nailuvar Sinaga
Marsal Risfandi
Ramlan Silaban
Year: 2019
Effects of Giving Red Fruit Oil on Creatinine and Urea Levels of Rats (Rattus Novergicus) on Maximal Physical Activity
AISTSSE
EAI
DOI: 10.4108/eai.18-10-2018.2287348
Abstract
Maximal physical activity can produce an imbalance between reactive oxygen species (ROS) and antioxidants which is possibly related to fatigue and tissue injury.This study investigated the effect of red fruit oil on serum creatinine and urea level in maximal physical activity.This study used posttest-only control group design. Twenty four rats were divided into 4 groups. The control group (I) was administered with 1.5 ml distilled water, intervention groups (II), (III) and (IV) were administered with different doses of Red Fruit Oil (0.15 ml, 0.3 ml, and 0.6 ml/kgBW, respectively for 30 day). All groups were trained to swim for 4 weeks and then were forced to swim without a load until being exhausted. The serum creatinine and urea levels were measured in all groups.The results showed that creatinine and urea level obtained was decreasing significantly (p=0.000) in the intervention groups. The results suggest that red fruit oil can obviously reduce creatinine and urea level induced by maximal physical activity in rat.
