Proceedings of The 5th Annual International Seminar on Trends in Science and Science Education, AISTSSE 2018, 18-19 October 2018, Medan, Indonesia

Research Article

Effects of Giving Red Fruit Oil on Creatinine and Urea Levels of Rats (Rattus Novergicus) on Maximal Physical Activity

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  • @INPROCEEDINGS{10.4108/eai.18-10-2018.2287348,
    author={Fajar Apollo Sinaga and Pangondian Hotliber Purba and Novita Sari Harahap and Rika Nailuvar Sinaga and Marsal Risfandi and Ramlan Silaban},
    title={Effects of Giving Red Fruit Oil on Creatinine and Urea Levels of Rats (Rattus Novergicus) on Maximal Physical Activity},
    proceedings={Proceedings of The 5th Annual International Seminar on Trends in Science and Science Education, AISTSSE 2018, 18-19 October 2018, Medan, Indonesia},
    publisher={EAI},
    proceedings_a={AISTSSE},
    year={2019},
    month={10},
    keywords={red fruit oil creatinine urea maximal physical activity},
    doi={10.4108/eai.18-10-2018.2287348}
}
  • Fajar Apollo Sinaga
    Pangondian Hotliber Purba
    Novita Sari Harahap
    Rika Nailuvar Sinaga
    Marsal Risfandi
    Ramlan Silaban
    Year: 2019
    Effects of Giving Red Fruit Oil on Creatinine and Urea Levels of Rats (Rattus Novergicus) on Maximal Physical Activity
    AISTSSE
    EAI
    DOI: 10.4108/eai.18-10-2018.2287348
Fajar Apollo Sinaga1,*, Pangondian Hotliber Purba1, Novita Sari Harahap1, Rika Nailuvar Sinaga1, Marsal Risfandi1, Ramlan Silaban2
  • 1: Department of Sports Sciences, Universitas Negeri Medan
  • 2: Department of Chemistry, Faculty of Mathematics and Natural Sciences, Universitas Negeri Medan
*Contact email: sinaga_fajar@yahoo.com

Abstract

Maximal physical activity can produce an imbalance between reactive oxygen species (ROS) and antioxidants which is possibly related to fatigue and tissue injury.This study investigated the effect of red fruit oil on serum creatinine and urea level in maximal physical activity.This study used posttest-only control group design. Twenty four rats were divided into 4 groups. The control group (I) was administered with 1.5 ml distilled water, intervention groups (II), (III) and (IV) were administered with different doses of Red Fruit Oil (0.15 ml, 0.3 ml, and 0.6 ml/kgBW, respectively for 30 day). All groups were trained to swim for 4 weeks and then were forced to swim without a load until being exhausted. The serum creatinine and urea levels were measured in all groups.The results showed that creatinine and urea level obtained was decreasing significantly (p=0.000) in the intervention groups. The results suggest that red fruit oil can obviously reduce creatinine and urea level induced by maximal physical activity in rat.

Keywords
red fruit oil creatinine urea maximal physical activity
Published
2019-10-04
Publisher
EAI
http://dx.doi.org/10.4108/eai.18-10-2018.2287348
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