Proceedings of The 5th Annual International Seminar on Trends in Science and Science Education, AISTSSE 2018, 18-19 October 2018, Medan, Indonesia

Research Article

Antibacterial Activity Analysis of Zanthoxylum Acanthopodium DC Extract on Bacteria of Bacillus Subtilis, and Salmonella Typhi

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  • @INPROCEEDINGS{10.4108/eai.18-10-2018.2287303,
        author={Nora Susanti Sihombing and Friska  Sihombing and Tita  Juwitaningsih and Destria  Roza and Donny M Pasaribu},
        title={Antibacterial Activity Analysis of Zanthoxylum Acanthopodium DC Extract on Bacteria of Bacillus Subtilis, and Salmonella Typhi},
        proceedings={Proceedings of The 5th Annual International Seminar on Trends in Science and Science Education, AISTSSE 2018, 18-19 October 2018, Medan, Indonesia},
        publisher={EAI},
        proceedings_a={AISTSSE},
        year={2019},
        month={10},
        keywords={zanthoxylum acanthopodium dc antibacterial disc diffusion},
        doi={10.4108/eai.18-10-2018.2287303}
    }
    
  • Nora Susanti Sihombing
    Friska Sihombing
    Tita Juwitaningsih
    Destria Roza
    Donny M Pasaribu
    Year: 2019
    Antibacterial Activity Analysis of Zanthoxylum Acanthopodium DC Extract on Bacteria of Bacillus Subtilis, and Salmonella Typhi
    AISTSSE
    EAI
    DOI: 10.4108/eai.18-10-2018.2287303
Nora Susanti Sihombing1,*, Friska Sihombing1, Tita Juwitaningsih1, Destria Roza1, Donny M Pasaribu1
  • 1: Chemistry Department, Faculty of Mathematics and Natural Science, State University of Medan, Jl. Willem Iskandar, Pasar V, Medan Estate, Medan, North Sumatera, Indonesia
*Contact email: nora.susanti.s2@gmail.com

Abstract

Research has been conducted on the antibacterial activity analysis of Zanthoxylum acanthopodium DC extract on Bacillus subtilis, Salmonella typhi using disc diffusion method. This study aims to determine the ability of Zanthoxylum acanthopodium DC extract in inhibiting the growth of Bacillus subtillis, and Salmonella typhi. Zanthoxylum acanthopodium DC was extracted by maceration method using 96% ethanol. In this extraction process, phytochemical test was carried out to find out the secondary metabolite content in Zanthoxylum acanthopodium DC. Phytochemical test indicate Zanthoxylum acanthopodium DC contained alkaloids, tannins, saponins, and steroids. Antibacterial activity analysis were measured in three concentrations of 25%, 50%, 75%. The best antibacterial activity was observed on Salmonella typhi bacteria with 75% extract concentration which produced a clear zone diameter of 19 mm and 20 mm.