Proceedings of the 1st International Seminar on Teacher Training and Education, ISTED 2021, 17-18 July 2021, Purwokerto, Indonesia

Research Article

Identification of Epicatechin Gallate and Other Phytochemicals in Methanol Extract of Fresh and Dried Star-Fruits (Averrhoa carambola Linn.) for Treatment of Type 2 Diabetes Mellitus

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  • @INPROCEEDINGS{10.4108/eai.17-7-2021.2312400,
        author={Yustika Sari and Dono Indarto and Brian Wasita},
        title={Identification of Epicatechin Gallate and Other Phytochemicals in Methanol Extract of Fresh and Dried Star-Fruits (Averrhoa carambola Linn.) for Treatment of Type 2 Diabetes Mellitus},
        proceedings={Proceedings of the 1st International Seminar on Teacher Training and Education, ISTED 2021, 17-18 July 2021, Purwokerto, Indonesia},
        publisher={EAI},
        proceedings_a={ISTED},
        year={2021},
        month={10},
        keywords={sodium-glucose co-transporter 2 inhibitor star fruits extract epicatechin gallate type 2 diabetes mellitus},
        doi={10.4108/eai.17-7-2021.2312400}
    }
    
  • Yustika Sari
    Dono Indarto
    Brian Wasita
    Year: 2021
    Identification of Epicatechin Gallate and Other Phytochemicals in Methanol Extract of Fresh and Dried Star-Fruits (Averrhoa carambola Linn.) for Treatment of Type 2 Diabetes Mellitus
    ISTED
    EAI
    DOI: 10.4108/eai.17-7-2021.2312400
Yustika Sari1, Dono Indarto2,*, Brian Wasita2
  • 1: Postgraduate Student of Clinical Nutrition, Universitas Sebelas Maret, Surakarta, Indonesia
  • 2: Universitas Sebelas Maret, Surakarta, Indonesia
*Contact email: dono@staff.uns.ac.id

Abstract

From an in-silico study, Averrhoa carambola L. (star fruit) contains epicatechin gallate (ECG), which has a similar effect to Sodium-glucose co transporter 2 (SGLT2) inhibitor. This study aimed to identify ECG and other phytochemicals in methanol extracts of fresh and dried star fruits. Ripened star-fruits (RSFs) were divided into two parts: directly extracted using methanol, while the other was dried and were then extracted using methanol. ECG and phytochemicals were identified using GC-MS, LC-MS and spectrophotometer. The yield of fresh RSFs extract was approximately double than that of dried RSFs extract. 4H-Pyran-4-one,2,3-dihydro-3,5-dihydroxy-6-methyl- was the highest phytochemicals in fresh RSFs extract whereas dried RSFs extract had glycerine. However, extract of dried RSFs had higher ECG levels than that of fresh RSFs (p=0.002). In conclusion, methanol extract of dried RSFs has higher ECG levels and different phytochemicals than fresh RSFs, which potentially become a diabetes herbal drug for an SGLT2 inhibitor.