Proceedings of the First International Conference on Science, Engineering and Technology Practices for Sustainable Development, ICSETPSD 2023, 17th-18th November 2023, Coimbatore, Tamilnadu, India

Research Article

Comparative study of greener and traditional extraction for the identification of sustainable phytocompounds from Simarouba glauca leaves for health benefits

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  • @INPROCEEDINGS{10.4108/eai.17-11-2023.2342855,
        author={Vanitha  Subburaj and Umaa  K and Veintramuthu  Sankar},
        title={Comparative study of greener and traditional extraction for the identification of sustainable phytocompounds from Simarouba glauca leaves for health benefits},
        proceedings={Proceedings of the First International Conference on Science, Engineering and Technology Practices for Sustainable Development, ICSETPSD 2023, 17th-18th November 2023, Coimbatore, Tamilnadu, India},
        publisher={EAI},
        proceedings_a={ICSETPSD},
        year={2024},
        month={1},
        keywords={greener extraction technique climatic change phytochemicals lc-ms/ms analysis simarouba glauca},
        doi={10.4108/eai.17-11-2023.2342855}
    }
    
  • Vanitha Subburaj
    Umaa K
    Veintramuthu Sankar
    Year: 2024
    Comparative study of greener and traditional extraction for the identification of sustainable phytocompounds from Simarouba glauca leaves for health benefits
    ICSETPSD
    EAI
    DOI: 10.4108/eai.17-11-2023.2342855
Vanitha Subburaj1,*, Umaa K2, Veintramuthu Sankar3
  • 1: Department of Pharmacognosy, PSG College of Pharmacy
  • 2: Department of Pharmaceutical Chemistry, PSG College of Pharmacy
  • 3: Department of Pharmaceutics, PSG College of Pharmacy
*Contact email: vanithas2002@gmail.com

Abstract

Emerging advancement in the discovery of novel phytochemical compounds from natural sources is a significant milestone in modern healthcare, aiding in the prevention and management of diseases for a healthy well being. One of the biggest issue currently experienced is the climatic change and its impact on human illnesses can be overcome by the sustainability of potential phytochemicals. The current study compares the best extraction efficiency from greener extraction compared to conventional extraction. Methanolic and aqueous leaf extracts of Simarouba glauca were prepared by greener extraction as well as conventional extraction method using 23 full factorial designs in order to optimize the maximum extraction efficiency in both the methods. The study found that the Ultrasonic Assisted Extraction had the highest extraction responses for both methanol (16%w/w) and aqueous (23%w/w) phases. The Soxhlet method produced good extraction responses for both methanol (13%w/w) and water (22%w/w). LC-MS/MS analysis identified the potential phytochemicals such as flavonoids and phenolic compounds (Hesperetin, Kaempferol, Fisetin and Dicaffeoyl quinolactone) in SG aqueous leaf extract. Similarly potential phytochemicals such as flavonoids, alkaloid, terpenoids, steroids and carotenoids were identified from SG methanol leaf extract. In futuristic study, the biological response of the identified potential phytochemicals from Simarouba glauca needs to be assessed for health benefits.