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Proceedings of the 7th International Conference on Innovation in Education, Science, and Culture, ICIESC 2025, 16 September 2025, Medan, Indonesia

Research Article

Isolation of Bioactive Flavonoid Compounds from the Sap of Sumatran Frankincense (Styrax benzoin) which have Potential as Medicinal Raw Materials

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  • @INPROCEEDINGS{10.4108/eai.16-9-2025.2361085,
        author={Manihar  Situmorang and Ruth Jessika Sinaga and Isnaini  Nurwahyuni and Hendra  Simanjuntak and Marudut  Sinaga and Bajoka  Nainggolan and Abd.  Hakim},
        title={Isolation of Bioactive Flavonoid Compounds from the Sap of Sumatran Frankincense (Styrax benzoin) which have Potential as Medicinal Raw Materials},
        proceedings={Proceedings of the 7th International Conference on Innovation in Education, Science, and Culture, ICIESC 2025, 16 September 2025, Medan, Indonesia},
        publisher={EAI},
        proceedings_a={ICIESC},
        year={2026},
        month={3},
        keywords={flavonoids; sumatran frankincense; styrax benzoin; bioactive compounds; medicinal compounds},
        doi={10.4108/eai.16-9-2025.2361085}
    }
    
  • Manihar Situmorang
    Ruth Jessika Sinaga
    Isnaini Nurwahyuni
    Hendra Simanjuntak
    Marudut Sinaga
    Bajoka Nainggolan
    Abd. Hakim
    Year: 2026
    Isolation of Bioactive Flavonoid Compounds from the Sap of Sumatran Frankincense (Styrax benzoin) which have Potential as Medicinal Raw Materials
    ICIESC
    EAI
    DOI: 10.4108/eai.16-9-2025.2361085
Manihar Situmorang1,*, Ruth Jessika Sinaga1, Isnaini Nurwahyuni2, Hendra Simanjuntak3, Marudut Sinaga1, Bajoka Nainggolan1, Abd. Hakim4
  • 1: Department of Chemistry, Faculty of Mathematics and Natural Sciences, Universitas Negeri Medan, Medan, North Sumatera, Indonesia, 20221
  • 2: Departement of Biology, Faculty of Mathematics and Natural Science, Universitas Sumatera Utara, North Sumatera, Indonesia, 20155
  • 3: Universitas HKBP Nommensen Pematangsiantar, Pematang Siantar, North Sumatera, INDONESIA, 78383
  • 4: Department of Physics, Faculty of Mathematics and Natural Sciences, Universitas Negeri Medan, Medan, North Sumatera, Indonesia, 20221
*Contact email: msitumorang@unimed.ac.id

Abstract

The flavonoid group as natural polyphenolic compounds produced by plants needs to be explored because they have medicinal properties. Sumatran Frankincense (Styrax benzoin) is known as a plant that produces incense resin containing bioactive substances which have been used as medicinal ingredients in traditional and modern medicine. These bioactive compounds from Sumatran forest plants need to be revealed to increase the economic value of non-timber forest products. The research aims to isolate flavonoids from Frankincense resin as a strategy to confirm the potential of Sumatran Frankincense as a source of bioactive compounds for medicinal raw materials. The research stages include isolating and identifying flavonoid compounds contained in frankincense sap. The research results demonstrated success in isolating bioactive flavonoids from frankincense sap using various types of solvents. Isolates have been identified qualitatively to confirm the presence of bioactive compounds in the flavonoid group. The pure isolate is in the form of a yellowish-white crystalline powder and has an aroma, soluble in alcohol solvents, soluble in hot water, and difficult to dissolve in cold water. boiling point 285 oC and melting point 81 oC. Initial analysis to identify the presence of flavonoids in the frankincense sap isolate was carried out using FTIR and showed the functional groups of the flavonoids contained in the frankincense sap.

Keywords
flavonoids; sumatran frankincense; styrax benzoin; bioactive compounds; medicinal compounds
Published
2026-03-18
Publisher
EAI
http://dx.doi.org/10.4108/eai.16-9-2025.2361085
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