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Proceedings of the 1st International Conference on Frontiers in Physical and Chemical Sciences: Exploring New Horizons, FPCS 2024, 13-14 November 2024, Bengaluru, Karnataka, India

Research Article

Formulating Cough Lozenges with Coleus amboinicus: A Phytotherapeutic Approach

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  • @INPROCEEDINGS{10.4108/eai.13-11-2024.2355689,
        author={Ambujakshi Hospet  Ramaiah and Venkatesh Dinnekere  Puttegowda and Ajay Pankajbhai  Lunagariya and Adnan Ali  M. M. and Simab  Akhtar and MD Amir Sohel  Refaquati and Md. Abdullah  Imam},
        title={Formulating Cough Lozenges with Coleus amboinicus: A Phytotherapeutic Approach},
        proceedings={Proceedings of the 1st International Conference on Frontiers in Physical and Chemical Sciences: Exploring New Horizons, FPCS 2024, 13-14 November 2024, Bengaluru, Karnataka, India},
        publisher={EAI},
        proceedings_a={FPCS},
        year={2025},
        month={8},
        keywords={coleus amboinicus herbal lozenges melting and molding techniques natural remedies},
        doi={10.4108/eai.13-11-2024.2355689}
    }
    
  • Ambujakshi Hospet Ramaiah
    Venkatesh Dinnekere Puttegowda
    Ajay Pankajbhai Lunagariya
    Adnan Ali M. M.
    Simab Akhtar
    MD Amir Sohel Refaquati
    Md. Abdullah Imam
    Year: 2025
    Formulating Cough Lozenges with Coleus amboinicus: A Phytotherapeutic Approach
    FPCS
    EAI
    DOI: 10.4108/eai.13-11-2024.2355689
Ambujakshi Hospet Ramaiah1,*, Venkatesh Dinnekere Puttegowda2, Ajay Pankajbhai Lunagariya2, Adnan Ali M. M.1, Simab Akhtar1, MD Amir Sohel Refaquati1, Md. Abdullah Imam1
  • 1: Department of Pharmacognosy, Acharya& BM Reddy College of Pharmacy, Bengaluru, Karnataka-560107 India
  • 2: Department of Pharmaceutics, Acharya& BM Reddy College of Pharmacy, Bengaluru, Karnataka-560107 India
*Contact email: ambujakshi@acharya.ac.in

Abstract

The present study focuses on the formulation and development of lozenges incorporating Coleus amboinicus juice for cough suppression. The Coleus amboinicus leaves were collected, prepared the herbal juice and preliminary phytochemical screening was conducted to assess its active constituents. Four lozenge formulations (F1 to F4) were developed by melting and molding technique, with varying sugar concentrations of 30 g, 40 g, 50 g and 60 g. The formulated lozenges were evaluated for organoleptic properties, weight variation, friability, moisture content, thickness, hardness, and stability test. Among the four formulations, F4 demonstrated superior performance in weight variation, friability, and hardness. Phytochemical analysis confirmed the presence of alkaloids and saponins in the herbal juice and the prepared lozenges, suggesting that these compounds may contribute to the lozenges' effectiveness in treating cough and throat irritation. This study demonstrates that the Coleus amboinicus lozenges, particularly formulation F4, provide an effective alternative to conventional cough remedies.

Keywords
coleus amboinicus, herbal lozenges, melting and molding techniques, natural remedies
Published
2025-08-15
Publisher
EAI
http://dx.doi.org/10.4108/eai.13-11-2024.2355689
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