Proceedings of the 1st EAI International Conference on Medical And Health Research, ICoMHER November 13-14th 2018, Padang, West Sumatera, Indonesia

Research Article

The Effect of Aloe vera Gel on Widal Titer of Rats Ingested Salmonella typhi Bacteria

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  • @INPROCEEDINGS{10.4108/eai.13-11-2018.2283658,
        author={Renowati  Renowati and Enlita  Enlita and Fitra  Wahyuni},
        title={The Effect of Aloe vera Gel on Widal Titer of Rats Ingested Salmonella typhi Bacteria},
        proceedings={Proceedings of the 1st EAI International Conference on Medical And Health Research, ICoMHER November 13-14th 2018, Padang, West Sumatera, Indonesia},
        publisher={EAI},
        proceedings_a={ICOMHER},
        year={2019},
        month={5},
        keywords={aloe vera gel male white rats salmonella widal agglutination titres},
        doi={10.4108/eai.13-11-2018.2283658}
    }
    
  • Renowati Renowati
    Enlita Enlita
    Fitra Wahyuni
    Year: 2019
    The Effect of Aloe vera Gel on Widal Titer of Rats Ingested Salmonella typhi Bacteria
    ICOMHER
    EAI
    DOI: 10.4108/eai.13-11-2018.2283658
Renowati Renowati1,*, Enlita Enlita1, Fitra Wahyuni2
  • 1: Medical laboratory technology department of Perintis Padang School of Health Science, Simp. Kalumpang, LubukBuaya, Padang
  • 2: Nursing department of Pekanbaru Medical Center School of Health Science, Lembaga Permasyarakatan No. 25, Gobah Pekanbaru, Riau
*Contact email: renowati01@yahoo.co.id

Abstract

Aloe vera was a traditional medicinal plant that can react as an adjuvant to increase the immune response to antigens because of that Aloe vera was called an immunomodulator. Salmonella typhi bacteria can be destroyed and eliminated by improving macrophage function. This can be done using immunostimulants that have a function as immunomodulators. One plant that acts as an immunostimulant is Aloe vera. The Widal test is one method that utilizes immunology to determine levels of antibodies in the serum, to help diagnose typhoid fever. Based on the description, a study was conducted to see the effect of Aloe vera gel on widal titer in rats that were ingested by Salmonella typhi. This study used white male rats (Rattusnorvegicus L.) strain Wistar, body weight 200 grams consisting of 4 groups with 2 treatments 7 times repetition, namely P1 (Aloe vera gel 1.8 ml/200g/Bw), P2 (Aloe vera gel 3.6 ml/200g/Bw), control (+) ingested Salmonella typhi bacteria and not using Aloe vera gel, (-) using distilled water. The collected data includes objectively tested data, namely Widal titers. The Mann Whitney test results showed that Aloe vera gel affected the decrease of tidal titer (antibodies) in white rats which had been indicated by Salmonella typhimurium bacteria (P <0.05)