Research Article
An Autonomous Molecular Transport System Using DNAs and Motor Proteins in Molecular Communication
@INPROCEEDINGS{10.4108/ICST.BIONETICS2007.2427, author={S. Hiyama and Y. Moritani and T. Suda and T. Shima and K. Sutoh}, title={An Autonomous Molecular Transport System Using DNAs and Motor Proteins in Molecular Communication}, proceedings={2nd International ICST Conference on Bio-Inspired Models of Network, Information, and Computing Systems}, proceedings_a={BIONETICS}, year={2008}, month={8}, keywords={Autonomous operation DNA Molecular communication Molecular transport system Motor protein}, doi={10.4108/ICST.BIONETICS2007.2427} }- S. Hiyama
Y. Moritani
T. Suda
T. Shima
K. Sutoh
Year: 2008
An Autonomous Molecular Transport System Using DNAs and Motor Proteins in Molecular Communication
BIONETICS
ICST
DOI: 10.4108/ICST.BIONETICS2007.2427
Abstract
This paper describes a molecular transport system in molecular communication that uses the machinery in living cells. The molecular transport system requires: 1) loading of the specified cargo molecules at a loading site (at a sender); 2) transport of the loaded cargoes to an unloading site (to a receiver); and 3) unloading of the transported cargoes at the unloading site, all without using external stimuli. Through the DNA strand exchange at a loading site and at an unloading site, and through motility of a biological motor system (kinesins and microtubules), the authors of this paper constructed a molecular transport system and demonstrated that kinesin-driven microtubules autonomously load, transport and unload cargoes to which a specified DNA strand is attached.
