Nano-Net. 4th International ICST Conference, Nano-Net 2009, Lucerne, Switzerland, October 18-20, 2009. Proceedings

Research Article

Information Transfer through Calcium Signaling

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  • @INPROCEEDINGS{10.1007/978-3-642-04850-0_4,
        author={Tadashi Nakano and Jian-Qin Liu},
        title={Information Transfer through Calcium Signaling},
        proceedings={Nano-Net. 4th International ICST Conference, Nano-Net 2009, Lucerne, Switzerland, October 18-20, 2009. Proceedings},
        proceedings_a={NANO-NET},
        year={2012},
        month={5},
        keywords={molecular communication calcium signaling channel capacity},
        doi={10.1007/978-3-642-04850-0_4}
    }
    
  • Tadashi Nakano
    Jian-Qin Liu
    Year: 2012
    Information Transfer through Calcium Signaling
    NANO-NET
    Springer
    DOI: 10.1007/978-3-642-04850-0_4
Tadashi Nakano1,*, Jian-Qin Liu2,*
  • 1: Osaka University
  • 2: National Institute of Information and Communications Technology
*Contact email: tnakano@wakate.frc.eng.osaka-u.ac.jp, liu@nict.go.jp

Abstract

In this paper, we discuss information transfer through calcium signaling, one form of molecular communication that is ubiquitously used in natural biological systems and that is potentially useful to design synthetic biological systems. We use a mathematical model to describe a molecular communication system in which a transmitter communicates information with the receiver over a calcium signaling channel. Mutual information between transmitter and receiver is then used to calculate the amount of information transfer from the transmitter to the receiver. An example simulation result is provided to illustrate how we measure the amount of information transferred over a calcium signaling channel. Our approach may further develop an understanding of design principles of biological systems as well as help design synthetic biological systems.