Research Article
Quantum Dots and Wires to Improve Enzymes-Based Electrochemical Bio-sensing
@INPROCEEDINGS{10.1007/978-3-642-04850-0_26, author={Sandro Carrara and Cristina Boero and Giovanni Micheli}, title={Quantum Dots and Wires to Improve Enzymes-Based Electrochemical Bio-sensing}, proceedings={4th International ICST Workshop on Nano-bio-sensing}, proceedings_a={NANO-BIO-SENSING}, year={2012}, month={5}, keywords={Quantum Dots Quantum Wires Gold Nano-Particles Carbon Nanotubes Oxidases Cytochromes Electrochemical detection}, doi={10.1007/978-3-642-04850-0_26} }- Sandro Carrara
Cristina Boero
Giovanni Micheli
Year: 2012
Quantum Dots and Wires to Improve Enzymes-Based Electrochemical Bio-sensing
NANO-BIO-SENSING
Springer
DOI: 10.1007/978-3-642-04850-0_26
Abstract
An investigation on nano-structured electrodes to detect different metabolites is proposed in this paper. Three different metabolites are considered: glucose, lactate, and cholesterol. The direct detection of hydrogen peroxide is also considered since it does not involve any enzyme. The metabolites and the peroxide were detected by using screen-printed electrodes modified by using multi-walled carbon nanotubes. In all cases, improvements of orders of magnitude were registered both on detection sensitivity and on detection limit. A close comparison with data recently published in literature has shown the existence of an inverse linear correlation between detection sensitivity and detection limit when sensor performances improve due to nano-structured materials. This inverse linear relationship seems to be a general law as it is here demonstrated for all the considered detections on glucose, lactate, cholesterol, and hydrogen peroxide.