A Cancer Diagnostics Biosensor System Based on Micro- and Nano-technologies

Pedro Ortiz; Neil Keegan; Julia Spoors; John Hedley; Alun Harris; Jim Burdess; Richie Burnett; Margit Biehl; Werner Haberer; Thomas Velten; Matthew Solomon; Andrew Campitelli; Calum McNeil

4th International ICST Workshop on Nano-bio-sensing

Research Article

A Cancer Diagnostics Biosensor System Based on Micro- and Nano-technologies

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@INPROCEEDINGS{10.1007/978-3-642-04850-0_24,
    author={Pedro Ortiz and Neil Keegan and Julia Spoors and John Hedley and Alun Harris and Jim Burdess and Richie Burnett and Margit Biehl and Werner Haberer and Thomas Velten and Matthew Solomon and Andrew Campitelli and Calum McNeil},
    title={A Cancer Diagnostics Biosensor System Based on Micro- and Nano-technologies},
    proceedings={4th International ICST Workshop on Nano-bio-sensing},
    proceedings_a={NANO-BIO-SENSING},
    year={2012},
    month={5},
    keywords={Lab-on-a-Chip microfluidics bioMEMS biosensors clinical diagnostics packaging},
    doi={10.1007/978-3-642-04850-0_24}
}

Pedro Ortiz
Neil Keegan
Julia Spoors
John Hedley
Alun Harris
Jim Burdess
Richie Burnett
Margit Biehl
Werner Haberer
Thomas Velten
Matthew Solomon
Andrew Campitelli
Calum McNeil
Year: 2012
A Cancer Diagnostics Biosensor System Based on Micro- and Nano-technologies
NANO-BIO-SENSING
Springer
DOI: 10.1007/978-3-642-04850-0_24

Pedro Ortiz¹^,*, Neil Keegan¹^,*, Julia Spoors¹, John Hedley¹, Alun Harris¹, Jim Burdess¹, Richie Burnett¹, Margit Biehl², Werner Haberer², Thomas Velten², Matthew Solomon³, Andrew Campitelli³, Calum McNeil¹

1: Newcastle University
2: Fraunhofer Institute for Biomedical Engineering (IBMT)
3: MiniFAB Pty Ltd.

*Contact email: p.m.ortiz@ncl.ac.uk, neil.keegan@ncl.ac.uk

Abstract

A biosensor system for medical diagnostics based around resonant MEMS sensor technology is presented in this paper. The working principle of the bioMEMS device is introduced and the functionalisation strategies for cancer marker recognition are described. In addition, the successful packaging and integration of functional MEMS biosensor devices are reported herein. This ongoing work represents one of the first hybrid assemblies to integrate a PCB packaged silicon MEMS device into a disposable microfluidic device.

Keywords: Lab-on-a-Chip microfluidics bioMEMS biosensors clinical diagnostics packaging

Published: 2012-05-28

: http://dx.doi.org/10.1007/978-3-642-04850-0_24