4th International ICST Workshop on Nano-bio-sensing

Research Article

A Cancer Diagnostics Biosensor System Based on Micro- and Nano-technologies

  • @INPROCEEDINGS{10.1007/978-3-642-04850-0_24,
        author={Pedro Ortiz and Neil Keegan and Julia Spoors and John Hedley and Alun Harris and Jim Burdess and Richie Burnett and Margit Biehl and Werner Haberer and Thomas Velten and Matthew Solomon and Andrew Campitelli and Calum McNeil},
        title={A Cancer Diagnostics Biosensor System Based on Micro- and Nano-technologies},
        proceedings={4th International ICST Workshop on Nano-bio-sensing},
        keywords={Lab-on-a-Chip microfluidics bioMEMS biosensors clinical diagnostics packaging},
  • Pedro Ortiz
    Neil Keegan
    Julia Spoors
    John Hedley
    Alun Harris
    Jim Burdess
    Richie Burnett
    Margit Biehl
    Werner Haberer
    Thomas Velten
    Matthew Solomon
    Andrew Campitelli
    Calum McNeil
    Year: 2012
    A Cancer Diagnostics Biosensor System Based on Micro- and Nano-technologies
    DOI: 10.1007/978-3-642-04850-0_24
Pedro Ortiz1,*, Neil Keegan1,*, Julia Spoors1, John Hedley1, Alun Harris1, Jim Burdess1, Richie Burnett1, Margit Biehl2, Werner Haberer2, Thomas Velten2, Matthew Solomon3, Andrew Campitelli3, Calum McNeil1
  • 1: Newcastle University
  • 2: Fraunhofer Institute for Biomedical Engineering (IBMT)
  • 3: MiniFAB Pty Ltd.
*Contact email: p.m.ortiz@ncl.ac.uk, neil.keegan@ncl.ac.uk


A biosensor system for medical diagnostics based around resonant MEMS sensor technology is presented in this paper. The working principle of the bioMEMS device is introduced and the functionalisation strategies for cancer marker recognition are described. In addition, the successful packaging and integration of functional MEMS biosensor devices are reported herein. This ongoing work represents one of the first hybrid assemblies to integrate a PCB packaged silicon MEMS device into a disposable microfluidic device.