Time Dependent Virus Replication in Cell Cultures

Juan Ochoa; Andreas Voigt; Heiko Briesen; Kai Sundmacher

Complex Sciences. First International Conference, Complex 2009, Shanghai, China, February 23-25, 2009. Revised Papers, Part 1

Research Article

Time Dependent Virus Replication in Cell Cultures

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@INPROCEEDINGS{10.1007/978-3-642-02466-5_63,
    author={Juan Ochoa and Andreas Voigt and Heiko Briesen and Kai Sundmacher},
    title={Time Dependent Virus Replication in Cell Cultures},
    proceedings={Complex Sciences. First International Conference, Complex 2009, Shanghai, China, February 23-25, 2009. Revised Papers, Part 1},
    proceedings_a={COMPLEX PART 1},
    year={2012},
    month={5},
    keywords={Virus Replication Influenza A Cellular viral Resistance},
    doi={10.1007/978-3-642-02466-5_63}
}

Juan Ochoa
Andreas Voigt
Heiko Briesen
Kai Sundmacher
Year: 2012
Time Dependent Virus Replication in Cell Cultures
COMPLEX PART 1
Springer
DOI: 10.1007/978-3-642-02466-5_63

Juan Ochoa^,*, Andreas Voigt, Heiko Briesen¹, Kai Sundmacher

1: Max Planck Institute for Complex Technical Systems

*Contact email: diaz@mpi-magdeburg.mpg.de

Abstract

We present in this report a stochastic model for the virus replication of influenza A in a cell culture. We consider not only the infection process of individual cells but also the number of intracellular components expressed in virus equivalent. Given that this expression is non constant in time we suggest a variable threshold, related to a viral resistance in the cell population, that could explain the time variation in the viral expression in the cell seen in experiments.

Keywords: Virus Replication Influenza A Cellular viral Resistance

Published: 2012-05-11

: http://dx.doi.org/10.1007/978-3-642-02466-5_63

Time Dependent Virus Replication in Cell Cultures

Abstract

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