Research Article
Organizational Structure of the Transcriptional Regulatory Network of Yeast: Periodic Genes
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@INPROCEEDINGS{10.1007/978-3-642-02466-5_12, author={Frank Emmert-Streib and Matthias Dehmer}, title={Organizational Structure of the Transcriptional Regulatory Network of Yeast: Periodic Genes}, proceedings={Complex Sciences. First International Conference, Complex 2009, Shanghai, China, February 23-25, 2009. Revised Papers, Part 1}, proceedings_a={COMPLEX PART 1}, year={2012}, month={5}, keywords={graph theory transcriptional regulatory network causality randomization periodic genes}, doi={10.1007/978-3-642-02466-5_12} }- Frank Emmert-Streib
Matthias Dehmer
Year: 2012
Organizational Structure of the Transcriptional Regulatory Network of Yeast: Periodic Genes
COMPLEX PART 1
Springer
DOI: 10.1007/978-3-642-02466-5_12
Abstract
In this paper we investigate the organizational structure of the transcriptional regulatory network of with respect to the connectivity structure of periodic genes. We demonstrate that the giant strongly connected component plays a prominent role serving as central connector for genes experimentally found to be periodically expressed during the cell cycle of yeast. Numerically, we find by randomization of the gene labels that this organizational structure is unlikely to be formed by chance.
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