Research Article
Optimization of Parameters for Electrochemical Detection: Computer Simulation and Experimental Study
@INPROCEEDINGS{10.1007/978-3-319-92213-3_34, author={Marko Živanović and Danijela Cvetković and Nenad Filipović}, title={Optimization of Parameters for Electrochemical Detection: Computer Simulation and Experimental Study}, proceedings={Future Access Enablers for Ubiquitous and Intelligent Infrastructures. Third International Conference, FABULOUS 2017, Bucharest, Romania, October 12-14, 2017, Proceedings}, proceedings_a={FABULOUS}, year={2018}, month={7}, keywords={Computer simulation Electrochemistry Optimization}, doi={10.1007/978-3-319-92213-3_34} }- Marko Živanović
Danijela Cvetković
Nenad Filipović
Year: 2018
Optimization of Parameters for Electrochemical Detection: Computer Simulation and Experimental Study
FABULOUS
Springer
DOI: 10.1007/978-3-319-92213-3_34
Abstract
It has been shown that for each electrochemical measurement it is necessary first to optimize all the parameters that influence the obtained electrochemical signal. This is a time-consuming process and that is why in this study we focused on the computer simulation of the influence of multiparameters on the electrochemical signal. Herein we used a model system of the electroreduction of ruthenium(III) salt on gold electrode in phosphate buffer solution. Ru is often used as redox probe for detection and understanding of nucleic acid hybridization on the electrodes. This study should reveal some new aspects of using the computer simulations in determining the optimal measuring conditions for detection of RNA/PNA hybridoms on the gold surface.