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Bio-inspired Information and Communications Technologies. 14th EAI International Conference, BICT 2023, Okinawa, Japan, April 11-12, 2023, Proceedings

Research Article

A Intelligent Nanorobots Fish Swarm Strategy for Tumor Targeting

Cite
BibTeX Plain Text
  • @INPROCEEDINGS{10.1007/978-3-031-43135-7_27,
        author={ShanChao Wen and Yue Sun and SiYang Chen and Yifan Chen},
        title={A Intelligent Nanorobots Fish Swarm Strategy for Tumor Targeting},
        proceedings={Bio-inspired Information and Communications Technologies. 14th EAI International Conference, BICT 2023, Okinawa, Japan, April 11-12, 2023, Proceedings},
        proceedings_a={BICT},
        year={2023},
        month={9},
        keywords={Tumor targeting Nanorobots swarm Biological gradient field Vascular network Swarm intelligence},
        doi={10.1007/978-3-031-43135-7_27}
    }
    
  • ShanChao Wen
    Yue Sun
    SiYang Chen
    Yifan Chen
    Year: 2023
    A Intelligent Nanorobots Fish Swarm Strategy for Tumor Targeting
    BICT
    Springer
    DOI: 10.1007/978-3-031-43135-7_27
ShanChao Wen1, Yue Sun2,*, SiYang Chen2, Yifan Chen1
  • 1: School of Life Science and Technology
  • 2: School of mechanical and electrical engineering
*Contact email: sunyuestc90@126.com

Abstract

This paper proposes a nanorobots fish swarm algorithm (NFSA) for tumor targeting. The alterations in the tumor microenvironment caused by tumor growth produce the biological gradient field (BGF), which is regulated by the adjacent tortuous and dense capillary network. NFSA is used to measure tumor-targeting efficiency in comparison to the benchmarks of Brute-force and the conventional gradient descent algorithm. Our goal is to increase the efficiency of targeting tumors in the early stages by using existing swarm intelligence algorithms to manipulate nanorobot swarms (NS) through magnetic fields. The extracorporeal observation system sensed the motion of NS under the influence of a BGF and then estimated the gradient of BGF. The invasive percolation algorithm models the vascular network to evaluate the performance of searching strategies. We also apply the exponential evolution step mechanism to boost the tumor-targeting efficiency of NFSA. The results show that NFSA has higher overall tumor targeting efficiency and a fast convergence property than previous algorithms. We hope that the NS in a multi-agent system could pave the way for challenges in tumor targeting.

Keywords
Tumor targeting Nanorobots swarm Biological gradient field Vascular network Swarm intelligence
Published
2023-09-25
Appears in
SpringerLink
http://dx.doi.org/10.1007/978-3-031-43135-7_27
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