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Bio-inspired Information and Communication Technologies. 12th EAI International Conference, BICT 2020, Shanghai, China, July 7-8, 2020, Proceedings

Research Article

A Cooperative Molecular Communication for Targeted Drug Delivery

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  • @INPROCEEDINGS{10.1007/978-3-030-57115-3_2,
        author={Yue Sun and Yutao Hsiang and Yifan Chen and Yu Zhou},
        title={A Cooperative Molecular Communication for Targeted Drug Delivery},
        proceedings={Bio-inspired Information and Communication Technologies. 12th EAI International Conference, BICT 2020, Shanghai, China, July 7-8, 2020, Proceedings},
        proceedings_a={BICT},
        year={2020},
        month={8},
        keywords={Molecular communication Cooperative communication Targeted drug delivery},
        doi={10.1007/978-3-030-57115-3_2}
    }
    
  • Yue Sun
    Yutao Hsiang
    Yifan Chen
    Yu Zhou
    Year: 2020
    A Cooperative Molecular Communication for Targeted Drug Delivery
    BICT
    Springer
    DOI: 10.1007/978-3-030-57115-3_2
Yue Sun,*, Yutao Hsiang, Yifan Chen, Yu Zhou
    *Contact email: sunyuestc90@126.com

    Abstract

    The lack of actively targeted nanoparticles and a low drug concentration in lesions are two of the main problems in drug delivery. This paper proposes a cooperative molecular communication system for drug delivery, electromagnetic control in the lead with bacteria followers. The leading particle is consisted by two function: could be controlled by electromagnetic field, and release attractant molecules. This cooperative scheme provides actively targeted ability by electromagnetic control, furthermore it expands the impact range of chemotactic substances to improve the chemotactic efficiency. To approach the specific position, this paper proposes electromagnetic field to control the nanoparticles, while bacteria could search the larger concentration positions and get closer to the leading particles. This paper develops mathematical modelling for the proposed model, as well as the self-adapted concentration gradient field searching algorithm. Finally, this paper performs biologically realistic simulation experiments to evaluate the performance of the proposed model .

    Keywords
    Molecular communication Cooperative communication Targeted drug delivery
    Published
    2020-08-11
    Appears in
    SpringerLink
    http://dx.doi.org/10.1007/978-3-030-57115-3_2
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