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Future Access Enablers for Ubiquitous and Intelligent Infrastructures. 4th EAI International Conference, FABULOUS 2019, Sofia, Bulgaria, March 28-29, 2019, Proceedings

Research Article

Optoelectronic Method for Increasing the Signal-to-Noise Ratio in Mass Spectrometry for Urinary Disulfoton Identification

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  • @INPROCEEDINGS{10.1007/978-3-030-23976-3_37,
        author={Genica Caragea and Radu Macovei and Paul Şchiopu and Marian Vlădescu and Florin Grama and Maria Neicu and Mihai Ionică},
        title={Optoelectronic Method for Increasing the Signal-to-Noise Ratio in Mass Spectrometry for Urinary Disulfoton Identification},
        proceedings={Future Access Enablers for Ubiquitous and Intelligent Infrastructures. 4th EAI International Conference, FABULOUS 2019, Sofia, Bulgaria, March 28-29, 2019, Proceedings},
        proceedings_a={FABULOUS},
        year={2019},
        month={9},
        keywords={GC-MS SIS Disulfoton Urine},
        doi={10.1007/978-3-030-23976-3_37}
    }
    
  • Genica Caragea
    Radu Macovei
    Paul Şchiopu
    Marian Vlădescu
    Florin Grama
    Maria Neicu
    Mihai Ionică
    Year: 2019
    Optoelectronic Method for Increasing the Signal-to-Noise Ratio in Mass Spectrometry for Urinary Disulfoton Identification
    FABULOUS
    Springer
    DOI: 10.1007/978-3-030-23976-3_37
Genica Caragea1, Radu Macovei, Paul Şchiopu2, Marian Vlădescu2, Florin Grama3, Maria Neicu4, Mihai Ionică,*
  • 1: Military-Medical Scientific Research Centre Bucharest
  • 2: University “Politehnica” of Bucharest
  • 3: Clinical Hospital “Colţea” Bucharest
  • 4: University for Medicine and Pharmacy “Carol Davila” Bucharest
*Contact email: mihaiionica56@gmail.com

Abstract

Mass spectrometry is an optoelectronic method of determining organic substances by comparing their mass spectrum with mass spectra found in system libraries. In the case of biological products, substances of interest, biotic or xenobiotics, may be “hidden” from the background of the analyzed matrix noise, which alters the major aspect of the mass spectrum obtained and faces the impossibility of their identification. A gas chromatograph coupled with mass spectrometer (GC-MS) Varian was used, to develop a selected ion monitoring (SIM) method for increasing the signal-to-noise ratio for identifying the disulfoton in urine samples.

Keywords
GC-MS SIS Disulfoton Urine
Published
2019-09-17
Appears in
SpringerLink
http://dx.doi.org/10.1007/978-3-030-23976-3_37
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